San Diego, California

Coastal California & Yosemite
New, Value Vacation

from $2,779.00 (USD)

Per Person

Oct 04, 2026
through Oct 13, 2026

More offers from Cosmos

Nights: 9

Price Per Night:$308.78 (USD)
(based on double occupancy, for comparison only)

Oct 04, 2026 through Oct 13, 2026

Location(s): San Francisco, San Francisco – Yosemite National Park – Oakhurst, Oakhurst – Yosemite National Park – Monterey, Monterey – 17 - Mile Drive – Carmel – Pismo Beach, Pismo Beach – Solvang – Santa Barbara – Los Angeles, Los Angeles, Los Angeles – Mission San Juan Capistrano – San Diego, San Diego, San Diego – Dana Point – Los Angeles

10 Days, featuring: Los Angeles–mission San Juan Capistrano–san Diego

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4-Day West Coast Getaway with San Diego
Roundtrip from Los Angeles

from $599.00 (USD)

Per Person

Nov 24, 2026
through Nov 28, 2026

More offers from Princess Cruises®

Nights: 4

Ship: Emerald Princess

Price Per Night:$149.75 (USD)
(based on double occupancy, for comparison only)

Nov 24, 2026 through Nov 28, 2026

Itinerary: Los Angeles, San Diego, Ensenada, Los Angeles

Other Categories Starting At:

Inside

$599.00
Cat:IF
149.75 per night

Outside

$680.00
Cat:OZ
170.00 per night

Balcony

$799.00
Cat:BF
199.75 per night

Suite

$949.00
Cat:ME
237.25 per night

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7-Day Classic California Coast
Roundtrip from Los Angeles

from $699.00 (USD)

Per Person

Mar 14, 2027
through Mar 21, 2027

More offers from Princess Cruises®

Nights: 7

Ship: Emerald Princess

Price Per Night:$99.86 (USD)
(based on double occupancy, for comparison only)

Mar 14, 2027 through Mar 21, 2027

Itinerary: Los Angeles, San Francisco, Santa Barbara, San Diego, Ensenada, Los Angeles

Other Categories Starting At:

Inside

$699.00
Cat:IF
99.86 per night

Outside

$777.00
Cat:OZ
111.00 per night

Balcony

$919.00
Cat:BF
131.29 per night

Suite

$1,289.00
Cat:ME
184.14 per night

More Details Contact Us

Ensenada, Cabo & Mazatlan
Roundtrip from San Diego, California

from $855.85 (USD)

Per Person

Feb 28, 2027
through Mar 07, 2027

More offers from Royal Caribbean International

Nights: 7

Ship: Serenade of the Seas

Price Per Night:$122.26 (USD)
(based on double occupancy, for comparison only)

Feb 28, 2027 through Mar 07, 2027

Itinerary: San Diego, California, Ensenada, Mexico, Cruising, Cabo San Lucas, Mexico, Mazatlan, Mexico, Cruising, San Diego, California

Other Categories Starting At:

Inside

$855.85
Cat:ZI
122.26 per night

Outside

$1,018.85
Cat:YO
145.55 per night

Balcony

$1,163.85
Cat:XB
166.26 per night

Suite

N/A

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Margaritaville Hotel San Diego Gaslamp Quarter
Hotel Rating: 4 stars

from $431.00 (USD)

Per Person

Aug 17, 2025
through Aug 20, 2025

More offers from Pleasant Holidays

Nights: 3

Price Per Night:$143.67 (USD)
(based on double occupancy, for comparison only)

Aug 17, 2025 through Aug 20, 2025

Location(s): San Diego

Margaritaville Hotel San Diego Gaslamp Quarter is a distinctly Southern Californian take on the beloved experiential brand.

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Panama Canal: Mexico & Costa Rica
Miami, Fl to San Diego, Ca

from $1,838.13 (USD)

Per Person

Dec 04, 2026
through Dec 19, 2026

More offers from Norwegian Cruise Line

Nights: 15

Ship: Norwegian Star

Price Per Night:$122.54 (USD)
(based on double occupancy, for comparison only)

Dec 04, 2026 through Dec 19, 2026

Itinerary: Miami, Fl, CARTAGENA COLOMBIA, Colon, Panama, Transit Panama Canal, At Sea, PUNTARENAS PUERTO CALDERA, COSTA RICA, Puerto Quetzal, Guatemala, Acapulco, Mexico, Cabo San Lucas, Mexico, San Diego, Ca

Cruise the incredible Panama Canal with Norwegian on a 15-day itinerary from Miami to San Diego on board Norwegian Star®. Climb ‘las murallas’ in Cartagena for unforgettable views of the harbor. From Panama City, visit the world-famous Panama Canal, a true wonder of modern engineering. In Puerto Quetzal, venture out to Antigua, a 90-minute trek to where 17th century colonial facades beckon and Guatemalan history comes alive.

Other Categories Starting At:

Inside

$1,838.13
Cat:IF
122.54 per night

Outside

$2,238.13
Cat:OK
149.21 per night

Balcony

$3,318.13
Cat:BF
221.21 per night

Suite

$3,918.13
Cat:MB
261.21 per night

More Details Contact Us

Mexican Riviera: Cabo San Lucas
Roundtrip from San Diego, Ca

from $577.23 (USD)

Per Person

Feb 07, 2026
through Feb 12, 2026

More offers from Norwegian Cruise Line

Nights: 5

Ship: Norwegian Jade

Price Per Night:$115.45 (USD)
(based on double occupancy, for comparison only)

Feb 07, 2026 through Feb 12, 2026

Itinerary: San Diego, Ca, Cabo San Lucas, Mexico, San Diego, Ca

Embark on a Mexico cruise to remember on a 5-day round-trip cruise from San Diego on board Norwegian Jade®. Come discover a new side of paradise in the Mexican Riviera. Journey to the jewel of the Baja Peninsula, Cabo San Lucas, famous for its world-class sportfishing, as well as its high-end resorts.

Other Categories Starting At:

Inside

$577.23
Cat:IF
115.45 per night

Outside

$677.23
Cat:OK
135.45 per night

Balcony

$797.23
Cat:BF
159.45 per night

Suite

$927.23
Cat:MA
185.45 per night

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Inca & Aztec Kingdoms
Lima/Machu Picchu (Callao) to San Diego

from $4,999.00 (USD)

Per Person

Feb 21, 2026
through Mar 07, 2026

More offers from Oceania Cruises

Nights: 14

Ship: Vista

Price Per Night:$357.07 (USD)
(based on double occupancy, for comparison only)

Feb 21, 2026 through Mar 07, 2026

Itinerary: Lima/Machu Picchu (Callao), Salaverry, Manta, Puntarenas, San Juan Del Sur, Acajutla, Acapulco, Cabo San Lucas, Ensenada, San Diego

Other Categories Starting At:

Inside

N/A

Outside

N/A

Balcony

$4,999.00
Cat:B4
357.07 per night

Suite

$8,249.00
Cat:PH2
589.21 per night

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30-Day Circle Hawaii & Sea Of Cortez
Roundtrip from San Diego

from $5,469.00 (USD)

Per Person

Nov 19, 2026
through Dec 19, 2026

More offers from Holland America Line

Nights: 30

Ship: Zaandam

Price Per Night:$182.30 (USD)
(based on double occupancy, for comparison only)

Nov 19, 2026 through Dec 19, 2026

Itinerary: San Diego, Kauai, Honolulu, Hilo, Kona, Kahului, Ensenada, San Diego, Cabo San Lucas, Loreto...

Other Categories Starting At:

Inside

$5,469.00
Cat:N
182.30 per night

Outside

$6,119.00
Cat:HH
203.97 per night

Balcony

N/A

Suite

$10,269.00
Cat:BC
342.30 per night

More Details Contact Us

14-Day Classic California Coast And Mexican Riviera
Roundtrip from San Diego, California, US

from $2,224.00 (USD)

Per Person

Nov 01, 2025
through Nov 15, 2025

More offers from Holland America Line

Nights: 14

Ship: Nieuw Amsterdam

Price Per Night:$158.86 (USD)
(based on double occupancy, for comparison only)

Nov 01, 2025 through Nov 15, 2025

Itinerary: San Diego, California, US, Avalon, California, US, Days At Sea, San Francisco, California, US, Days At Sea, Ensenada, Mexico, San Diego, California, US, Days At Sea, Puerto Vallarta, Mexico, Mazatlan, Mexico...

Other Categories Starting At:

Inside

$2,224.00
Cat:N
158.86 per night

Outside

$2,354.00
Cat:HH
168.14 per night

Balcony

$2,784.00
Cat:VH
198.86 per night

Suite

$4,804.00
Cat:SZ
343.14 per night

More Details Contact Us

15-Day Panama Canal
San Diego, California, US to Miami, Florida, US

from $2,844.00 (USD)

Per Person

Feb 27, 2026
through Mar 14, 2026

More offers from Holland America Line

Nights: 15

Ship: Zuiderdam

Price Per Night:$189.60 (USD)
(based on double occupancy, for comparison only)

Feb 27, 2026 through Mar 14, 2026

Itinerary: San Diego, California, US, Days At Sea, Puerto Vallarta, Mexico, Days At Sea, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Days At Sea, Fuerte Amador, Panama, Enter Panama Canal Balboa...

Other Categories Starting At:

Inside

$2,844.00
Cat:N
189.60 per night

Outside

$2,944.00
Cat:HH
196.27 per night

Balcony

$3,944.00
Cat:VH
262.93 per night

Suite

$5,444.00
Cat:SZ
362.93 per night

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Pacific Coast Cruise: Vancouver, Seattle & San Francisco

from $2,079.00 (USD)

Per Person

May 17, 2027
through May 24, 2027

More offers from Azamara

Nights: 7

Ship: Azamara Quest

Price Per Night:$297.00 (USD)
(based on double occupancy, for comparison only)

May 17, 2027 through May 24, 2027

Itinerary: Vancouver, Seattle, Victoria, Astoria, San Francisco, San Diego

Other Categories Starting At:

Inside

$2,079.00
Cat:12
297.00 per night

Outside

$2,429.00
Cat:08
347.00 per night

Balcony

$2,989.00
Cat:V3
427.00 per night

Suite

$4,349.00
Cat:N2
621.29 per night

More Details Contact Us

11-Day Mexican Riviera & Pacific Coast
San Diego to Vancouver

from $1,914.00 (USD)

Per Person

Apr 25, 2026
through May 06, 2026

More offers from Holland America Line

Nights: 11

Ship: Zaandam

Price Per Night:$174.00 (USD)
(based on double occupancy, for comparison only)

Apr 25, 2026 through May 06, 2026

Itinerary: San Diego, Cabo San Lucas, Mazatlan, Puerto Vallarta, San Diego, Avalon, Vancouver

Other Categories Starting At:

Inside

$1,914.00
Cat:N
174.00 per night

Outside

$2,064.00
Cat:HH
187.64 per night

Balcony

N/A

Suite

$3,614.00
Cat:BC
328.55 per night

More Details Contact Us

32-Day Tahiti, Hawaii & South Pacific Crossing
Sydney to Vancouver

from $3,256.00 (USD)

Per Person

Mar 28, 2027
through Apr 28, 2027

More offers from Princess Cruises®

Nights: 32

Ship: Royal Princess

Price Per Night:$101.75 (USD)
(based on double occupancy, for comparison only)

Mar 28, 2027 through Apr 28, 2027

Itinerary: Sydney, Tauranga, Auckland, X Intl Date Line, Tahiti (Papeete), Moorea, Kona, Honolulu, Los Angeles, San Diego...

Other Categories Starting At:

Inside

$3,256.00
Cat:IE
101.75 per night

Outside

N/A

Balcony

$4,007.00
Cat:DW
125.22 per night

Suite

$6,598.00
Cat:ME
206.19 per night

More Details Contact Us

11-Day Mexican Riviera & Sea Of Cortez
Roundtrip from San Diego

from $2,014.00 (USD)

Per Person

Apr 07, 2026
through Apr 18, 2026

More offers from Holland America Line

Nights: 11

Ship: Zaandam

Price Per Night:$183.09 (USD)
(based on double occupancy, for comparison only)

Apr 07, 2026 through Apr 18, 2026

Itinerary: San Diego, Cruising Bahia Magda, Cabo San Lucas, La Paz, Loreto, Mazatlan, Puerto Vallarta, Manzanillo, San Diego

Other Categories Starting At:

Inside

$2,014.00
Cat:N
183.09 per night

Outside

$2,164.00
Cat:HH
196.73 per night

Balcony

N/A

Suite

$3,714.00
Cat:BC
337.64 per night

More Details Contact Us

14-Day Panama Canal
Miami to San Diego

from $3,449.00 (USD)

Per Person

Jan 02, 2027
through Jan 16, 2027

More offers from Holland America Line

Nights: 14

Ship: Zuiderdam

Price Per Night:$246.36 (USD)
(based on double occupancy, for comparison only)

Jan 02, 2027 through Jan 16, 2027

Itinerary: Miami, Cartagena, Panama Canal (Cruising), Enter Panama Canal Cristobal, Exit Panama Canal Balboa, Puntarenas, Puerto Quetzal, Huatulco, Acapulco, Cabo San Lucas...

Other Categories Starting At:

Inside

$3,449.00
Cat:N
246.36 per night

Outside

$3,749.00
Cat:HH
267.79 per night

Balcony

$4,549.00
Cat:VH
324.93 per night

Suite

$5,649.00
Cat:SZ
403.50 per night

More Details Contact Us

San Diego To London Grand Voyage

from $7,529.00 (USD)

Per Person

May 24, 2027
through Jun 28, 2027

More offers from Azamara

Nights: 35

Ship: Azamara Quest

Price Per Night:$215.11 (USD)
(based on double occupancy, for comparison only)

May 24, 2027 through Jun 28, 2027

Itinerary: San Diego, Cabo San Lucas, Acapulco, Puerto Quetzal, Acajutla, Puntarenas, Panama Canal (Cruising), Cartagena, Miami, Florida, New York City, New York...

Other Categories Starting At:

Inside

$7,529.00
Cat:12
215.11 per night

Outside

$8,859.00
Cat:08
253.11 per night

Balcony

$11,459.00
Cat:V3
327.40 per night

Suite

$18,059.00
Cat:N2
515.97 per night

More Details Contact Us

33-Day Grand Australia & New Zealand
Sydney to San Diego

from $7,004.00 (USD)

Per Person

Mar 06, 2026
through Apr 08, 2026

More offers from Holland America Line

Nights: 33

Ship: Zaandam

Price Per Night:$212.24 (USD)
(based on double occupancy, for comparison only)

Mar 06, 2026 through Apr 08, 2026

Itinerary: Sydney, Cruising Fiordland Np, Milford Sound, Port Chalmers (Dunedin), Timaru, Wellington, Tauranga, Auckland, Waitangi (Bay Of Islands), Nuku' Alofa...

Other Categories Starting At:

Inside

$7,004.00
Cat:N
212.24 per night

Outside

$7,764.00
Cat:HH
235.27 per night

Balcony

N/A

Suite

$17,554.00
Cat:BC
531.94 per night

More Details Contact Us

13-Day Mexican Riviera & Pacific Coast
Vancouver, B.C., CA to San Diego, California, US

from $1,994.00 (USD)

Per Person

Sep 28, 2025
through Oct 11, 2025

More offers from Holland America Line

Nights: 13

Ship: Nieuw Amsterdam

Price Per Night:$153.38 (USD)
(based on double occupancy, for comparison only)

Sep 28, 2025 through Oct 11, 2025

Itinerary: Vancouver, B.C., CA, Victoria, British Columbia, Canada, Days At Sea, San Francisco, California, US, Days At Sea, San Diego, California, US, Ensenada, Mexico, Days At Sea, Cabo San Lucas, Mexico, Puerto Vallarta, Mexico...

Other Categories Starting At:

Inside

$1,994.00
Cat:N
153.38 per night

Outside

$2,094.00
Cat:HH
161.08 per night

Balcony

$2,444.00
Cat:VH
188.00 per night

Suite

$4,244.00
Cat:SZ
326.46 per night

More Details Contact Us

San Diego, California (19 offers included)